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KMID : 1035620200080010045
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Allergy Asthma & Respiratory Disease
2020 Volume.8 No. 1 p.45 ~ p.49
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A case of IgG4-related disease associated with psoriasis-like skin rash and hypereosinophilic syndrome
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Park Han-Ki
Han Man-Hoon
Lee Sang-Jin
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Abstract
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Immunoglobulin (Ig) G4-related disease (IgG4-RD) is newly recognized immune-mediated and fibroinflammatory conditions with various organ involvements. Any organs can be involved, but the pancreas, salivary gland, lymph nodes, and orbit are known to be commonly involved organs. A 54-year-old man presented with complaint of psoriasis like skin rash developed 4 years prior to admission. Although he had been treated for skin rash, the extent of skin lesions increased as well as hypereosinophilia, and multiple lymphadenopathies were newly developed. The patient was diagnosed with IgG4-RD by serum IgG4 levels and histologic examination of the inguinal lymph node. One month after treatment with steroid and azathioprine, his skin rash and lymphadenopathies resolved with improvement and eosinophil count was within the normal range. We herein report a case of a IgG4-RD patient associated with psoriasis-like skin rash and hypereosinophilic syndrome.
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KEYWORD
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IgG4-related disease, Psoriasis, Hypereosinophilic syndrome
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